Misspent youth

So, thanks to lampbane, a little while back I got turned on to 30 Rock, and lately I've been watching it on DVD through Netflix. I just got done watching the DVD commentary on the last episode of season 2. In that episode, mention is made of "bull semen." In the commentary, Jane Krakowski wonders aloud if they're allowed to say "bull semen" on TV. Jack McBrayer mocks her for asking, since the dialogue was aired, so clearly they must be allowed. Krakowski then jokes that she thinks "bull semen" may have never been mentioned before on TV.

Friends, I just happen to know that it has. Further, I that know this mention took place on an NBC sitcom. I suppose you have to wonder what that says about NBC. Regardless, this is now an open call to you guys: do you know what I'm talking about?

This is, really, more of a two-part question.

Part one, in which I ask you to name the sitcom in question, is not actually a test of your sitcom knowledge. It's a test of how well you know what sitcom I've developed an disturbing and unnatural level of familiarity with. :)

Part two you can use to actually test your sitcom knowledge. What was the situation?